TABLE 2.
Total posaconazole concentrations in serum and plasma samples and concentrations in samples received from pediatric hospitalsa
| Population | No. of levels measured | Concn range (μg/ml) | Median quantifiable concn (μg/ml) | % of measurements below LLQ (<0.125 μg/ml) | % of measurements below 0.5 μg/ml | % of measurements below 0.7 μg/ml | % of measurements below 1.25 μg/ml |
|---|---|---|---|---|---|---|---|
| Total | 1,548 | Undetectable–6.57 | 0.64 | 9.60 | 34.60 | 58.40 | 81.10 |
| Pediatric | 152 | Undetectable–3.99 | 0.52 | 12.50 | 54.60 | 63.80 | 80.30 |
a
Concentrations were measured by HPLC. LLQ, lower limit of quantification.