TABLE 1.
Hematological profile for guinea pigs after chronic treatment with GRFTa
| Cell type | Parameter | Unit | Values |
|||
|---|---|---|---|---|---|---|
| Day 11 |
Day 15 |
|||||
| PBS (n = 3) | GRFT (n = 5) | PBS (n = 3) | GRFT (n = 5) | |||
| Leukocyte | WBC | k/μl | 4.92 ± 2.43 | 2.15 ± 0.23 | 4.35 ± 1.28 | 2.90 ± 1.36 |
| NE | k/μl | 2.30 ± 1.46 | 0.96 ± 0.13 | 1.67 ± 0.45 | 1.01 ± 0.42 | |
| LY | k/μl | 2.49 ± 1.11 | 1.14 ± 0.28 | 2.60 ± 0.89 | 1.82 ± 0.99 | |
| MO | k/μl | 0.09 ± 0.10 | 0.03 ± 0.03 | 0.07 ± 0.03 | 0.06 ± 0.04 | |
| EO | k/μl | 0.03 ± 0.02 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.01 ± 0.02 | |
| BA | k/μl | 0.00 ± 0.01 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | |
| Erythrocyte | RBC | M/μl | 4.30 ± 0.06 | 4.12 ± 0.18 | 4.75 ± 0.21 | 4.37 ± 0.22 |
| Hb | g/dl | 12.23 ± 0.64 | 11.64 ± 0.46 | 13.10 ± 0.46 | 12.22 ± 0.61 | |
| HCT | % | 38.30 ± 2.31 | 36.12 ± 1.47 | 41.57 ± 1.76 | 39.52 ± 1.94 | |
| MCV | fl | 88.97 ± 4.73 | 87.58 ± 1.29 | 87.53 ± 1.70 | 90.40 ± 0.52* | |
| MCH | pg | 28.43 ± 1.33 | 28.26 ± 1.52 | 27.63 ± 0.61 | 27.96 ± 1.04 | |
| MCHC | g/dl | 31.97 ± 0.25 | 32.26 ± 1.33 | 31.50 ± 0.26 | 30.94 ± 1.11 | |
| RDW | % | 13.83 ± 1.43 | 12.92 ± 0.73 | 14.13 ± 0.29 | 12.66 ± 0.70* | |
| Thrombocyte | PLT | k/μl | 595.33 ± 54.31 | 628.60 ± 44.77 | 677.33 ± 11.93 | 659.00 ± 34.26 |
| MPV | fl | 4.40 ± 1.14 | 3.92 ± 0.23 | 3.57 ± 0.12 | 3.84 ± 0.24 | |
a
Data represent the mean values ± standard deviations for white blood cells (WBC), neutrophils (NE), lymphocytes (LY), monocytes (MO), eosinophils (EO), basophils (BA), red blood cells (RBC), hemoglobin (Hb), hematocrit (HCT), mean corpuscular volume (MCV), mean cell hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), red cell distribution width (RDW), platelets (PLT), and mean platelet volume (MPV). Statistical significance (P < 0.05) is indicated by asterisks (*).