FIG 3.

Effect of treatment of L. infantum-infected BALB/c mice with commercial (Glu) or synthetic (MA) meglumine antimoniate using different liver parameters: A, lucent area in hepatocytes; B, apoptotic index of hepatocytes; and C, peroxidase activity. Mice were treated with Glu or MA (80 mg of Sb/kg/day) or saline for 20 days by the i.p. route. Noninfected mice receiving saline were also used as controls. The data are means ± the standard errors of the mean (SEM; n = 3 to 7). ***, P < 0.001 (one-way ANOVA with Bonferroni post test).