FIG 4.

Influence of AA on the liver parameters of L. infantum-infected BALB/c mice treated or not to with commercial meglumine antimoniate (Glu). The liver parameters measured included the percentage of lucent area in the hepatocytes (A), the apoptotic index of the hepatocytes (B), and the peroxidase activity (C). Mice were treated with Glu (80 mg/kg/day), AA (15 mg/kg/day), Glu+AA, or saline alone for 20 days by the i.p. route. Data are means ± the SEM (n = 3 to 7). ***, P < 0.001; **, P < 0.01 (one-way ANOVA with Bonferroni post test).