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. 2014 Jan;58(1):577–580. doi: 10.1128/AAC.01674-13

TABLE 2.

C. glabrata strains displaying non-HS FKS alterationsa

Isolate Yr Source MIC (μg/ml)
FKS alterationb
FKS1 HS1 FKS2 HS1 FKS2 HS2 Non-HS
Micafungin Anidulafungin Caspofungin Fluconazole FKS1 FKS2
46228A 2011 South Africa 0.015 0.06 0.25 128 Neg Neg Neg Y1279F T926P
49889F 2011 Canada 0.015 0.03 0.25 32 Neg Neg Neg Neg G680S
10729J 2004 United Kingdom 0.015 0.06 0.25 1 Neg Neg Neg L195F Neg
10685J 2004 Spain 0.015 0.06 0.25 32 Neg Neg Neg Neg F384Y
10702J 2005 Spain 0.015 0.12 0.25 16 Neg Neg Neg A995T Neg
10728J 2002 Spain 0.015 0.06 0.25 1 Neg Neg Neg D140Y, A1749V Neg
44075F 2011 Washington 0.03 0.06 0.12 32 Neg Neg Neg Neg T926P
17823F 2011 Michigan 0.06 0.12 0.06 128 Neg Neg Neg Neg A450T
10708J 2005 Poland 0.06 0.25 0.25 16 Neg Neg Neg A1749V Neg
760F 2008 Washington 0.12 0.5 0.25 4 Neg S663F Neg Neg T926P
37706F 2011 United States 0.5 1 0.5 8 Neg S663Y Neg Neg G680S
10700J 2004 Japan 0.5 2 1 64 Neg L662W Neg Neg E78D, T926P
49079F 2011 Australia 2 2 2 >128 Neg S663P Neg Neg T926P
a

Strains were collected from 2001 to 2011 in two global surveillance studies.

b

Neg, Negative.