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Tissue/blood hydroxychloroquine concentration ratios in rabbits
| Time (min) after drug administration | Ratio of hydroxychloroquine concn in following tissue to that in blood: |
|||||
|---|---|---|---|---|---|---|
| Popliteal lymph nodes | Submandibular lymph nodes | Femoral lymph nodes | Prescapular lymph nodes | Splenic lymph nodes | Peyer's patches | |
| 20 | 9.89 | 25.96 | 19.52 | 51.44 | 26.28 | 163.11 |
| 60 | 2.77 | 5.46 | 3.67 | 7.15 | 13.02 | 3.59 |
| 180 | 9.30 | 13.61 | 8.09 | 4.30 | 10.56 | 10.46 |
| 480 | 7.90 | 8.74 | 7.43 | 3.66 | 44.77 | 9.92 |
| 840 | 15.44 | 7.87 | 13.19 | 77.09 | 9.87 | |
