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Histopathological analysis of spleen during A. actinomycetemcomitans bacteremic conditions treated with hLF. Histopathology of LFKO−/− mouse spleen. Arrows show the morphological changes in the spleen section. Shown are results for the following treatment groups: (A) PBS, (B) hLF only, C) bacteria only, (D) oral feeding of hLF, (E) prophylactic hLF i.v. administration, (F) concurrent hLF i.v. administration, and (G) therapeutic hLF i.v. administration.
