TABLE 4.
Change in spleen weight during A. actinomycetemcomitans bacteremia
| LFKO−/− mouse treatment group | Spleen wt (mg)a |
|---|---|
| LFKO−/− control | 58.6 ± 3.17 |
| hLF alone | 63.5 ± 0.76 |
| Bacteria only | 381.2 ± 3.32* (P < 0.003) |
| hLF oral feeding | 259 ± 12.31 |
| Prophylactic | 74.3 ± 7.20* (P < 0.03) |
| Therapeutic | 81.3 ± 5.5* (P < 0.001) |
| Concurrent | 68.8 ± 8.97* (P < 0.04) |
a
Spleens of mice (n = 8) were dissected 96 h postinfection, and their weights were measured. Values are presented as means ± SEM. *, significant (P < 0.05) difference from the control and/or the hLF treatment group, as calculated by Student's t test.