TABLE 2.
Activity of 10 μM GSK2336805 on a panel of RNA and DNA viruses
| Virus | % Reduction in CPE | % Cell viability |
|---|---|---|
| Adenovirus type 1 | 35.2 | 100 |
| Adenovirus type 3 | 2.4 | 100 |
| Adenovirus type 40 | 6.5 | 99.6 |
| BVDV | 10.3 | 100 |
| Coxsackie A7 virus | 3.8 | 98.8 |
| Coxsackie B4 virus | 1.5 | 98.5 |
| Dengue virus strain 1 | 0 | 99.1 |
| Dengue virus strain 2 | 3.1 | 98.1 |
| Dengue virus strain 3 | 3.8 | 95.8 |
| Dengue virus strain 4 | 4.5 | 94.6 |
| Enterovirus | 9.5 | 98.3 |
| Herpes simplex virus 1 | 7.2 | 95 |
| Herpes simplex virus 2 | 3.1 | 97 |
| Influenza A virus | 4.5 | 99.4 |
| Influenza B virus | 3 | 100 |
| Measles virus | 1.2 | 100 |
| Parainfluenza virus | 0 | 94.8 |
| Poliovirus | 2.2 | 99.3 |
| Respiratory syncytial virus | 26.8 | 99.6 |
| Rhinovirus | 29.7 | 100 |
| Rotavirus | 0 | 97.4 |
| Yellow fever virus | 2.4 | 98.6 |