TABLE 1.
Collection period | Urinary pH |
Volume (ml) |
||
---|---|---|---|---|
Mean ± SD | Median (range) | Mean ± SD | Median (range) | |
Before dosing | 6.5 ± 0.8 | 6.2 (5.8–7.9) | 1,039 ± 281 | 1,029 (702–1,409) |
After nitroxoline (250 mg) | ||||
0–4 h | 6.9 ± 0.6 | 6.9 (6.3–8.0) | 878 ± 375 | 983 (346–1,362) |
4–8 h | 6.4 ± 0.6a | 6.7 (5.6–7.0) | 639 ± 276 | 593 (252–1,002) |
8–12 h | 6.8 ± 0.4 | 6.8 (6.3–7.5) | 783 ± 368 | 804 (322–1,302) |
12–24 h | 6.3 ± 0.5 | 6.5 (5.5–6.7) | 1,072 ± 595 | 924 (579–2,210) |
After trimethoprim (200 mg) | ||||
0–4 h | 7.3 ± 0.2 | 7.3 (6.9–7.6) | 1,076 ± 401 | 1,165 (327–1,452) |
4–8 h | 7.2 ± 0.4a | 7.3 (6.7–7.5) | 711 ± 387 | 630 (355–1,413) |
8–12 h | 6.8 ± 0.3 | 6.9 (6.3–7.2) | 924 ± 300 | 900 (466–1,259) |
12–24 h | 6.3 ± 0.5 | 6.2 (5.7–7.1) | 1,207 ± 688 | 1,108 (328–2,277) |
Statistically significant (P < 0.05).