TABLE 9.

Metabolite analysis of trimethoprim in the urine of 6 volunteers at 0 to 24 h

Metabolite	Metabolite reaction	Relative area (%)
Trimethoprim	NAa	89.4
M1	+O	7.4
M2	−CH2	1.2
M3	+C6H8O6	0.8
M4	+C6H8O7	0.2
M5	−CH2+SO3	0.3
M6	−CH2+C6H8O6	0.8

^aNA, not applicable.