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Intracellular stavudine triphosphate (d4T-TP) concentrations at steady state. Points represent actual data for compliant patients from Becher et al. (20). The shaded area and line represent the 95% prediction interval and median of the simulation in pediatric patients administered 0.5 mg/kg twice daily (left) and in adult patients administered 20 mg twice daily (center) and 40 mg twice daily (right).
