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. 2014 Feb;58(2):1167–1178. doi: 10.1128/AAC.01855-13

TABLE 6.

Blood parasitemia AUCs in the murine in vivo efficacy experiments

Treatment Dose (mg/kg) % parasitemia AUC relative to vehicle control (mean ± SD)
Expt 1 Expt 2
Untreated 0 100 ± 33 100 ± 21
Benznidazole 50 32 ± 23 44 ± 9
Cz007 3 NDa 16 ± 3
10 ND 44 ± 10
50 ND 46 ± 8
Cz008 3 ND 23 ± 6
10 10 ± 2 25 ± 7
50 35 ± 30 ND
a

ND, not determined.