FIG 1.
Cre-Lox HCV reporter platform for cell-based HTS assay. (A) Schematic representation of HCV-Cre and pCAG-LoxPGluc constructs. The junctional sequences containing two NS3-NS4A cleavage sites (arrows) flanking the Cre gene are shown. (B) Diagram of HCV-Cre infection and Gluc production in Huh7.5.1.LoxPGLuc cells.