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IL-2 (a) and IFN-γ (b) responses to PPDB following BCG vaccination and then challenge with M. bovis (experiment 2). Results are compared with those of an unvaccinated challenge control group. Data show the group mean and standard error for each group at each time point (n = 4 unvaccinated; n = 5 BCG vaccinated). Significantly higher IL-2 and IFN-γ levels were observed in challenge control cattle than in vaccinated cattle at 4 weeks after M. bovis challenge.
