FIG 7.

Prominent F. tularensis epitopes detected in serum samples from vesicle-immunized mice are conserved across multiple strains of F. tularensis. F. tularensis from strains Schu S4, MA00-2987 (A1 strains), WY96-3418 (A2 strain), KY99-3387, OR96-0246, and LVS (B strains) were grown in enriched TSB as described in Materials and Methods and subjected to Western analysis (4 to 20% gradient gel) with the antisera used in Fig. 5 and 6. (A) Sera from LVS-V-immunized mice before challenge. (B) Sera from LVS-V-immunized mice after live LVS challenge. (C) Sera from Schu S4-immunized mice after live Schu S4 challenge.