FIG 4.

Neutralizing activity associated with gB-G eVLP-induced monoclonal antibodies. Two commercially available gB-specific MAbs generated using HCMV extracts (catalog no. 54023, Abcam, and catalog no. C9100-21N, United States Biological, for MAbs no. 1 and no. 2, respectively), and the gB-G eVLP-induced clones 7B3 and 7B9 were tested for neutralizing activity against HCMV infection of fibroblasts and epithelial cells. All antibodies were tested at identical dilutions ranging from 10 μg/ml to 0.1 μg/ml. The lowest antibody concentrations associated with 50% neutralization activity are shown.