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. 2014 Jan;80(1):154–165. doi: 10.1128/AEM.03108-13

TABLE 4.

NC- and CL-enriched genes in E. faecium

Genea P valuesb Product(s) Strain group enriched
Ortholog_4462 0.00139 Hypothetical protein NC
Ortholog_5797 (fnr-1) 0.00139 Crp/Fnr family transcriptional regulator NC
Ortholog_6667 0.00139 Hypothetical protein NC
Ortholog_3053 0.00189 Hypothetical protein NC
Ortholog_2935 0.00281 Hypothetical protein NC
Ortholog_3142 0.00281 Hypothetical membrane protein NC
Ortholog_3722 0.00281 NAD-dependent epimerase/dehydratase NC
Ortholog_522 0.00281 Hypothetical 3-demethylubiquinone-9 3-methyltransferase NC
Ortholog_568 (thiJ) 0.00281 ThiJ/PfpI, C56 or DJ-1/PfpI family intracellular protease/amidase, hypothetical chaperone protein HSP31 NC
Ortholog_197 (epsB) 0.00411 Undecaprenyl-phosphate galactosephosphotransferase, glucosyltransferase EpsB, galactosyltransferase NC
Ortholog_2934 (cobO) 0.00411 Cob(I)alamin adenosyltransferase NC
Ortholog_302 0.00411 Cobalamin ECF transporter, lipoprotein NC
Ortholog_3930 (cbrT) 0.00411 Substrate-specific component CbrT of cobalamin ECF transporter NC
Ortholog_5083 0.00411 Hypothetical protein NC
Ortholog_57 0.00411 Adenosylcobalamin (coenzyme B12)-dependent ribonucleoside-diphosphate reductase NC
Ortholog_2421 (dps) 0.00554 Non-specific DNA-binding protein Dps, iron-binding ferritin-like antioxidant protein/ferroxidase NC
Ortholog_4208 (copZ) 0.00554 Copper chaperone copZ, heavy metal-associated domain, MerTP family mercury (Hg2+) permease NC
Ortholog_2070 0.00595 Hypothetical protein NC
Ortholog_4672 0.00595 Hypothetical protein NC
Ortholog_476 0.00595 HTH ArsR-type DNA-binding transcriptional regulator NC
Ortholog_2867 0.00799 Transposase IS3/IS911 CL
Ortholog_2905 0.00799 Hypothetical protein CL
Ortholog_4275 0.00799 Hypothetical protein CL
Ortholog_507 0.00799 Hypothetical protein CL
Ortholog_5905 0.00799 IS3-family transposase, integrase, transposase InsK, IS150-like transposase CL
Ortholog_6476 0.00799 Hypothetical protein CL
Ortholog_3968 0.00883 Hypothetical protein CL
Ortholog_4531 0.00883 Hypothetical protein CL
Ortholog_1362 0.00925 D12 class N6 adenine-specific DNA methyltransferase NC
Ortholog_1422 (cps4F) 0.00925 Capsular polysaccharide biosynthesis protein Cps4F, glycosyl transferase group 1 NC
Ortholog_1609 0.00925 Hypothetical protein NC
Ortholog_1712 0.00925 UDP-glucose 4-epimerase, NAD-dependent epimerase/dehydratase NC
Ortholog_3751 0.00925 Hypothetical protein NC
Ortholog_3762 (mga) 0.00925 M protein trans-acting positive regulator (MGA) NC
Ortholog_5644 (capD) 0.00925 Polysaccharide biosynthesis protein CapD, NAD-binding protein, UDP-glucose 4-epimerase NC
Ortholog_5738 0.00925 Hypothetical protein NC
Ortholog_5837 (wecB) 0.00925 UDP-N-acetylglucosamine 2-epimerase NC
Ortholog_6592 (cap5F) 0.00925 NAD-dependent epimerase/dehydratase, capsular polysaccharide biosynthesis protein Cap5F NC
Ortholog_6669 0.00925 Hypothetical protein NC
a

Full sets of NC- or CL-enriched genes are listed in Table S3 in the supplemental material.

b

P values were obtained by Fisher's exact test.