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Schematic illustration of engineering mussel-inspired catecholamine-displayed E. coli. DOPA and histidine repeats found in the mussel adhesive protein, Mefp-5, are displayed on the E. coli surface using outer membrane protein W (OmpW) as the anchoring motif. Since DOPA is an unnatural amino acid, tyrosine was displayed first and converted to DOPA using tyrosinase.
