TABLE 1.

Multiple comparisons of Cox mixed-effects survival models^a

Microbiota compared	Cox statistic for time to:
	Pupation				Eclosion
	Estimateb	SE	z value	P value	Estimateb	SE	z value	P value
A. pomorum–axenic	1.327	0.059	22.324	<0.001	1.178	0.060	19.634	<0.001
A. tropicalis–axenic	1.476	0.059	25.114	<0.001	1.538	0.060	25.595	<0.001
5-Species–axenic	1.250	0.059	21.324	<0.001	0.974	0.059	16.507	<0.001
L. brevis–axenic	0.389	0.057	6.797	<0.001	0.334	0.059	5.694	<0.001
L. fructivorans–axenic	−0.007	0.057	−0.119	1	0.013	0.058	0.225	1
L. plantarum–axenic	0.352	0.058	6.105	<0.001	0.266	0.059	4.521	<0.001
A. tropicalis–A. pomorum	0.150	0.059	2.537	0.14	0.360	0.060	6.034	<0.001
5-Species–A. pomorum	−0.077	0.059	−1.307	0.84	−0.204	0.060	−3.412	0.01
L. brevis–A. pomorum	−0.937	0.059	−15.826	<0.001	−0.844	0.060	−14.087	<0.001
L. fructivorans–A. pomorum	−1.334	0.059	−22.493	<0.001	−1.165	0.060	−19.534	<0.001
L. plantarum–A. pomorum	−0.975	0.060	−16.380	<0.001	−0.912	0.060	−15.175	<0.001
5-Species–A. tropicalis	−0.227	0.058	−3.889	0.001	−0.564	0.060	−9.466	<0.001
L. brevis–A. tropicalis	−1.087	0.058	−18.608	<0.001	−1.204	0.060	−20.191	<0.001
L. fructivorans–A. tropicalis	−1.483	0.059	−25.303	<0.001	−1.525	0.060	−25.538	<0.001
L. plantarum–A. tropicalis	−1.125	0.059	−19.080	<0.001	−1.272	0.060	−21.216	<0.001
L. brevis–5-species	−0.860	0.059	−14.670	<0.001	−0.640	0.059	−10.784	<0.001
L. fructivorans–5-species	−1.257	0.058	−21.484	<0.001	−0.961	0.059	−16.358	<0.001
L. plantarum–5-species	−0.898	0.059	−15.254	<0.001	−0.708	0.060	−11.907	<0.001
L. fructivorans–L. brevis	−0.396	0.057	−6.928	<0.001	−0.321	0.058	−5.497	<0.001
L. plantarum–L. brevis	−0.038	0.057	−0.656	0.99	−0.068	0.059	−1.159	0.90
L. plantarum–L. fructivorans	0.358	0.058	6.232	<0.001	0.253	0.059	4.316	<0.001

^aThe Cox model makes a global comparison of development observations, using experimental replicate as a random effect. Pairwise comparisons of the Cox models were made by Tukey's HSD test implemented in the multcomp package for R, adjusting P values for multiple comparisons using the default (single-step) method.

^bRestricted maximum likelihood estimate of the coefficient.