Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic illustration for the temperature-dependent functional importance of the three major periplasmic chaperones SurA, Skp, and FkpA for OMP biogenesis: SurA > Skp > FkpA at the normal temperature and FkpA ≥ SurA > Skp at the heat shock temperature. Sec, the essential SecYEG system for OMP translocation across the inner membrane; Bam, the essential BamABCDE complex for OMP assembly and insertion into the outer membrane.
