TABLE 1.
Isolates used in this studya
| ISE-SNP type | Culture no. | Country of origin | Administration division |
Source | YOI | Remark | ||
|---|---|---|---|---|---|---|---|---|
| First level | Second level | Third level | ||||||
| 1 | ITM_940511 | Ivory Coast | Moyen-Cavally | Duékoué | Niambli | ITM | 1994 | |
| 1 | ITM_000483 | Ivory Coast | Moyen-Cavally | Duékoué | Niambli | ITM | 2000 | |
| 1 | ITM_000870 | Ivory Coast | Dix-Huit Montagnes | Zouan-Hounien | Ouyatouo | ITM | 2000 | |
| 1 | ITM_063519 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Cité Songololo | IME | 2006 | |
| 1 | ITM_071924 | Congo | Kouilou | Madingo-Kayes | Loukouala | ITM | 2007 | Originated from same patient as 071925 |
| 1 | ITM_071925 | Congo | Kouilou | Madingo-Kayes | Loukouala | ITM | 2007 | Originated from same patient as 071924 |
| 1 | ITM_072398 | DRC | Bas-Congo | Cataractes/Songololo | Bamboma/Mbanza-Manteke | IME | 2007 | |
| 1 | ITM_072401 | DRC | Bas-Congo | Cataractes/Songololo | Palabala/Nkamuna | IME | 2007 | |
| 1 | ITM_072732 | DRC | Bas-Congo | Cataractes/Songololo | Palabala/Nkamuna | IME | 2007 | |
| 1 | ITM_072733 | DRC | Bas-Congo | Cataractes/Songololo | Luima-Mayanga/Ngombe | IME | 2007 | |
| 1 | ITM_072734 | DRC | Bas-Congo | Cataractes/Songololo | Bamboma/Mbanza-Manteke | IME | 2007 | |
| 1 | ITM_072735 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Luvuvamu | IME | 2007 | |
| 1 | ITM_072840 | DRC | Bas-Congo | Cataractes/Songololo | Palabala/Nkamuna | IME | 2007 | Originated from same patient as 072841 |
| 1 | ITM_072841 | DRC | Bas-Congo | Cataractes/Songololo | Palabala/Nkamuna | IME | 2007 | Originated from same patient as 072840 |
| 1 | ITM_073453 | DRC | Bas-Congo | Cataractes/Songololo | Palabala/Nkamuna | IME | 2007 | |
| 1 | ITM_073459 | Benin | Kouffo | Lalo | Ahojinako | CDTUB Lalo | 2007 | |
| 1 | ITM_073463 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Kisonga | IME | 2007 | |
| 1 | ITM_073477 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Cité Songololo | IME | 2007 | |
| 1 | ITM_073478 | Angola | Malanje | Marimba | Kafufu/Luremo (Kwango River) | IME | 2007 | |
| 1 | ITM_073479 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Kisonga | IME | 2007 | |
| 1 | ITM_082600 | DRC | Bas-Congo | Cataractes/Songololo | Kilueka/Nzundu | IME | 2008 | |
| 1 | ITM_100140 | DRC | Bas-Congo | Cataractes/Songololo | Lovo/Tole | IME | 2010 | |
| 1 | ITM_100141 | DRC | Bas-Congo | Cataractes/Songololo | Mayanga/Mpelo | IME | 2010 | Originated from same patient as 100141 |
| 1 | ITM_100142 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Luvuvamu | IME | 2010 | Originated from same patient as 100142 |
| 1 | ITM_100832 | DRC | Bas-Congo | Cataractes/Songololo | Palabala/Nkamuna | IME | 2010 | |
| 1 | ITM_100833 | DRC | Bas-Congo | Cataractes/Songololo | Mayanga/Mpelo | IME | 2010 | |
| 1 | ITM_032481 | DRC | Bas-Congo | Cataractes/Songololo | Luima/Nkondo-Kiomba | IME | 2003 | |
| 1 | ITM_040149 | Ghana | Ashanti | Asante Akim North | Agogo Presbyterian Hospital | ITM | 2003 | |
| 1 | ITM_991591 | Togo | Maritime | Vo | Anagali | ITM | 1999 | |
| 1 | ITM_050303 | Congo | Kouilou | ITM | 1979 | Originated from same patient as 050304 | ||
| 1 | ITM_050304 | Congo | Kouilou | ITM | 1979 | Originated from same patient as 050303 | ||
| 1 | ITM_960658 | Angola | Bengo | Dande | Caxito | ITM | 1996 | Originated from same patient as 960657 |
| 1 | ITM_960657 | Angola | Bengo | Dande | Caxito | ITM | 1996 | Originated from same patient as 960658 |
| 1 | ITM_072662 | Ghana | Ashanti | Asante Akim North | Ananekrom | KCCR | 2007 | |
| 1 | ITM_072646 | Ghana | Ashanti | Atwima Mponua | Abofrom | KCCR | 2007 | |
| 1 | ITM_072651 | Ghana | Ashanti | KMA | Kaase | KCCR | 2007 | |
| 1 | ITM_120140 | Cameroon | Adamawa Region | Maya-Banyo | Bankim/Mbondji II | CPC | 2011 | |
| 1 | ITM_030950 | Benin | Kouffo | Lalo | Adoukandji | CDTUB Lalo | 2003 | |
| 1 | ITM_030716 | Benin | Kouffo | Lalo | Tchito/Village Aboeti | CDTUB Lalo | 2003 | |
| 1 | ITM_102686 | Nigeria | Oyo State | Ibadan | Ibadan | ITM | 2010 | |
| 1 | ITM_083232 | Angola | Lunda Norte | Xa-Muteba | Kwango River | ITM | 2008 | |
| 1 | ITM_000869 | Ivory Coast | Moyen-Cavally | Duékoué | Guezon | ITM | 2000 | |
| 1 | ITM_990007 | Ivory Coast | Haut-Sassandra | Issia | Guetuzon II | ITM | 1998 | |
| 1 | ITM_991633 | Ivory Coast | Moyen-Cavally | Duékoué | Guezon | ITM | 1999 | |
| 2 | ITM_030791 | Benin | Kouffo | Lalo | Tchito/Gare | CDTUB Zagnanado | 2003 | |
| 2 | ITM_970680 | Benin | Mono | Houéyogbé | Sahoué | CDTUB Lalo | 1997 | |
| 2 | ITM_022876 | Benin | Kouffo | Lalo | Tohou | CDTUB Lalo | 2002 | |
| 2 | ITM_021434 | Benin | Kouffo | Klouékanmè | Adjassagon | CDTUB Lalo | 2002 | |
| 2 | ITM_012596 | Benin | Mono | Bopa | Lobogo | CDTUB Lalo | 2001 | |
| 2 | ITM_071938 | Benin | Kouffo | Lalo | Tandji | CDTUB Lalo | 2007 | |
| 4 | ITM_5150 | DRC | Bandundu | Kwilu | ITM | 1962 | ||
| 5 | ITM_940512 | Benin | Zou | Ouinhi | Ouokon | CDTUB Zagnanado | 1994 | |
| 5 | ITM_010157 | Benin | Zou | Zogbodomè | Domè-Houandougon | CDTUB Zagnanado | 2001 | |
| 5 | ITM_000951 | Benin | Zou | Zogbodomè | Domè-Houandougon | CDTUB Zagnanado | 2000 | |
| 5 | ITM_970435 | Benin | Ouémé | Bonou | Bonou | CDTUB Zagnanado | 1997 | Originated from same patient as 970301 |
| 5 | ITM_970301 | Benin | Ouémé | Bonou | Bonou | CDTUB Zagnanado | 1997 | Originated from same patient as 970435 |
| 5 | ITM_000479 | Benin | Zou | Zagnanado | Zagnanado/Doga | CDTUB Zagnanado | 2000 | |
| 5 | ITM_092100 | Benin | Zou | Zagnanado | Doga-Domè | CDTUB Zagnanado | 2009 | |
| 5 | ITM_083865 | Benin | Zou | Ouinhi | Tohoue/Hounnoumè | CDTUB Zagnanado | 2008 | |
| 5 | ITM_093013 | Benin | Zou | Ouinhi | Ouinhi/Monzoungoudo | CDTUB Zagnanado | 2009 | |
| 5 | ITM_093695 | Benin | Zou | Ouinhi | Ouinhi/Monzoungoudo | CDTUB Zagnanado | 2009 | |
| 5 | ITM_101300 | Benin | Zou | Ouinhi | Sagon/Adamè | CDTUB Zagnanado | 2010 | |
| 5 | ITM_101302 | Benin | Zou | Ouinhi | Dasso/Bossa | CDTUB Zagnanado | 2010 | |
| 5 | ITM_102554 | Benin | Zou | Ouinhi | Dasso/Agonkon | CDTUB Zagnanado | 2010 | |
| 5 | ITM_081919 | Benin | Zou | Ouinhi | Dasso/Yaago and Akantomè | CDTUB Zagnanado | 2008 | |
| 5 | ITM_092997 | Benin | Zou | Djidja | Oungbègame | CDTUB Zagnanado | 2009 | |
| 5 | ITM_080066 | Benin | Zou | Ouinhi | Sagon/Ayizè | CDTUB Zagnanado | 2008 | |
| 5 | ITM_070381 | Benin | Zou | Ouinhi | Dasso/Yaago | CDTUB Zagnanado | 2007 | |
| 5 | ITM_073151 | Benin | Zou | Ouinhi | Ouinhi/Monzoungoudo | CDTUB Zagnanado | 2007 | |
| 5 | ITM_070131 | Benin | Zou | Zagnanado | Dovi-Dove/Tévedji | CDTUB Zagnanado | 2007 | |
| 5 | ITM_092473 | Benin | Zou | Ouinhi | Tohoue/Midjannangon | CDTUB Zagnanado | 2009 | |
| 5 | ITM_082549 | Benin | Zou | Ouinhi | Tohoue/Akassa | CDTUB Zagnanado | 2008 | |
| 5 | ITM_090149 | Benin | Zou | Zagnanado | Dovi-Dove/Tévedji | CDTUB Zagnanado | 2009 | |
| 5 | ITM_091800 | Benin | Zou | Ouinhi | Tohoue/Gangban | CDTUB Zagnanado | 2009 | |
| 5 | ITM_083584 | Benin | Zou | Ouinhi | Ouinhi/Ahicon | CDTUB Zagnanado | 2008 | |
| 5 | ITM_9146 | Benin | Zou | Zagnanado | Kpedekpo/Loko-Alankpe | CDTUB Zagnanado | 1992 | |
| 5 | ITM_991721 | Benin | Atlantique | Toffo | Séhoué | CDTUB Zagnanado | 1999 | |
| 5 | ITM_092472 | Benin | Atlantique | Toffo | Séhoué/Agaga | CDTUB Zagnanado | 2009 | |
| 5 | ITM_070383 | Benin | Ouémé | Dangbo | Dékin | CDTUB Zagnanado | 2007 | |
| 5 | ITM_070625 | Nigeria | Ogun State | Yewa North | Odja Odan | CDTUB Zagnanado | 2007 | |
| 5 | ITM_061509 | Benin | Zou | Zagnanado | Zagnanado | CDTUB Zagnanado | 2006 | |
| 5 | ITM_081676 | Benin | Plateau | Adja-Ouere | Tatonnoukon | CDTUB Zagnanado | 2008 | |
| 5 | ITM_081681 | Benin | Plateau | Issaba | Onigbolo | CDTUB Zagnanado | 2008 | |
| 5 | ITM_082696 | Benin | Ouémé | Adjohoun | Abato | CDTUB Zagnanado | 2008 | |
| 5 | ITM_091801 | Benin | Zou | Zogbodomè | Kpokissa/Hinzounmè | CDTUB Zagnanado | 2009 | |
| 5 | ITM_092101 | Benin | Ouémé | Dangbo | Gbéko | CDTUB Zagnanado | 2009 | |
| 5 | ITM_093694 | Benin | Ouémé | Dangbo | Gbéko | CDTUB Zagnanado | 2009 | |
| 5 | ITM_100126 | Benin | Zou | Zogbodomè | Kpokissa | CDTUB Zagnanado | 2010 | |
| 5 | ITM_951009 | Benin | Zou | Zagnanado | CDTUB Zagnanado | 1995 | ||
| 6 | ITM_5151 | DRC | Maniema | Kasongo | ITM | 1972 | ||
| 7 | ITM_970359 | Ghana | Ashanti | Amansie West | Manso-Afraso | ITM | 1997 | |
| 7 | ITM_970606 | Ghana | Ashanti | Amansie West | Yaw Kasakrom | ITM | 1997 | |
| 7 | ITM_970677 | Ghana | Ashanti | Amansie West | Manso Dominase | ITM | 1997 | |
| 7 | ITM_970678 | Ghana | Ashanti | Asante Akim North | Afrisre | ITM | 1997 | |
| 7 | ITM_970959 | Ghana | Ashanti | Amansie West | Manso-Afraso | ITM | 1997 | |
| 7 | ITM_970964 | Ghana | Ashanti | Amansie West | Offinho Asaman | ITM | 1997 | |
| 7 | ITM_971351 | Ghana | Ashanti | Atwima Mponua | Achiase | ITM | 1997 | |
| 7 | ITM_980063 | Ghana | Ashanti | Atwima Mponua | Achiase | ITM | 1998 | |
| 7 | ITM_940662 | Ivory Coast | Moyen-Cavally | Duékoué | Nanandi | ITM | 1994 | |
| 7 | ITM_990006 | Ivory Coast | Haut-Sassandra | Issia | Guetuzon I | ITM | 1998 | |
| 7 | ITM_990734 | Ivory Coast | Moyen-Cavally | Duékoué | Duékoué | ITM | 1999 | |
| 7 | ITM_991632 | Ivory Coast | Haut-Sassandra | Issia | Bediegbeu | ITM | 1999 | |
| 7 | ITM_072634 | Ghana | Ashanti | Asante Akim North | Adoniem | KCCR | 2007 | |
| 7 | ITM_072652 | Ghana | Ashanti | Atwima Mponua | Achiase | KCCR | 2007 | |
| 7 | ITM_072654 | Ghana | Ashanti | Atwima Mponua | Achiase | KCCR | 2007 | |
| 7 | ITM_072657 | Ghana | Ashanti | Atwima Mponua | Achiase | KCCR | 2007 | |
| 7 | ITM_072658 | Ghana | Western Region | Wassa West | Owusukrom | KCCR | 2007 | |
| 7 | ITM_072650 | Ghana | Ashanti | Atwima Nwabiagya | Kyereyase | KCCR | 2007 | |
| 7 | ITM_072630 | Ghana | Central | Upper Denkyira | Nkotumso | KCCR | 2007 | |
| 7 | ITM_072656 | Ghana | Ashanti | Atwima Mponua | Abompe | KCCR | 2007 | |
| 7 | ITM_072655 | Ghana | Ashanti | Atwima Mponua | Sireso | KCCR | 2007 | |
| 7 | ITM_072653 | Ghana | Ashanti | Atwima Mponua | Amadaa | KCCR | 2007 | |
| 7 | ITM_072645 | Ghana | Ashanti | Atwima Mponua | Achiase | KCCR | 2007 | |
| 12 | ITM_072814 | Benin | Ouémé | Dangbo | Gbéko | CDTUB Zagnanado | 2007 | |
| 13 | ITM_021433 | Benin | Kouffo | Lalo | Gnizoumè/Hangbanou | CDTUB Lalo | 2002 | |
| 13 | ITM_022045 | Benin | Kouffo | Lalo | Adoukandji/Yamontouhoué | CDTUB Lalo | 2002 | |
| 13 | ITM_022287 | Benin | Zou | Agbangnizoun | Kpota | CDTUB Lalo | 2002 | |
| 13 | ITM_022875 | Benin | Kouffo | Lalo | Gnizoumè | CDTUB Lalo | 2002 | |
| 13 | ITM_030717 | Benin | Kouffo | Lalo | Ahomadégbé | CDTUB Lalo | 2003 | |
| 13 | ITM_030718 | Benin | Kouffo | Lalo | Lalo | CDTUB Lalo | 2003 | |
| 13 | ITM_031892 | Benin | Kouffo | Lalo | Hlassamè | CDTUB Lalo | 2003 | |
| 13 | ITM_071804 | Benin | Kouffo | Lalo | Zalli | CDTUB Lalo | 2007 | |
| 14 | ITM_991590 | Togo | Maritime | Vo | Tchekpo Deve | ITM | 1999 | Originated from same patient as 000909 |
| 14 | ITM_000909 | Togo | Maritime | Vo | Tchekpo Deve | ITM | 2000 | Originated from same patient as 991590 |
| 14 | ITM_993354 | Togo | Maritime | Vo | Tchekpo Deve | ITM | 1999 | |
| 14 | ITM_042407 | Togo | Maritime | Vo | Kodji Kopé | ITM | 2004 | |
| 15 | ITM_070404 | DRC | Bas-Congo | Cataractes/Songololo | Kimpese/Cité-Kimpese | IME | 2007 | Originated from same patient as 070123 |
| 15 | ITM_070123 | DRC | Bas-Congo | Cataractes/Songololo | Kimpese/Cité-Kimpese | IME | 2007 | Originated from same patient as 070404 |
| 15 | ITM_092479 | DRC | Bas-Congo | Cataractes/Songololo | Kimpese/Cité-Kimpese | IME | 2009 | |
| 16 | ITM_990008 | Ivory Coast | Haut-Sassandra | Issia | Zakogbeu | ITM | 1998 | |
| 18 | ITM_070386 | Nigeria | Anambra State | Ayamelum | Ifite Ogwari | ITM | 2007 | |
| 19 | ITM_001211 | Ivory Coast | Dix-Huit Montagnes | Zouan-Hounien | Zouan-Hounien | ITM | 2000 | |
| 20 | ITM_020279 | Cameroon | Centre Region | Nyong-et-Mfoumou | Ayos | CPC | 2002 | |
| 20 | ITM_091067 | Gabon | Moyen-Ogooué | Ogooue et des Lacs | Junkville | ITM | 2009 | |
| 20 | ITM_110450 | Gabon | Moyen-Ogooué | Ogooue et des Lacs | Gravier | ITM | 2011 | |
| 22 | ITM_020280 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akolo | CPC | 2002 | |
| 22 | ITM_120542 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
| 23 | ITM_021081 | Cameroon | Centre Region | Nyong-et-Mfoumou | Obis | CPC | 2002 | |
| 23 | ITM_9102 | Cameroon | Centre Region | ITM | 1970 | |||
| 23 | ITM_9103 | Cameroon | Centre Region | ITM | 1970 | |||
| 23 | ITM_101500 | Gabon | Moyen-Ogooué | Ogooue et des Lacs | Lambaréné/Adaghe | ITM | 2010 | |
| 23 | ITM_110893 | Gabon | Moyen-Ogooué | Ogooue et des Lacs | Issac | ITM | 2011 | |
| 23 | ITM_120138 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2010 | |
| 23 | ITM_120139 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga/Wouma | CPC | 2011 | |
| 23 | ITM_120141 | Cameroon | Centre Region | Nyong-et-Mfoumou | Medjap | CPC | 2011 | |
| 23 | ITM_120142 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga/Ekolman | CPC | 2011 | |
| 23 | ITM_120534 | Cameroon | Centre Region | Nyong-Et-Soo | Bembé | CPC | 2011 | |
| 23 | ITM_120535 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
| 23 | ITM_120536 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga/Djo'o | CPC | 2011 | |
| 23 | ITM_120538 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
| 23 | ITM_120539 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
| 23 | ITM_120543 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
| 23 | ITM_120143 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
| 24 | ITM_051459 | Uganda | Northern Region | Adjumani | Adjumani | NCTC | 2005 | |
| 25 | ITM_120537 | Cameroon | Centre Region | Nyong-Et-Soo | Edjom | CPC | 2011 | |
| 26 | ITM_120540 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akam-Engali | CPC | 2011 | |
| 27 | ITM_120541 | Cameroon | Centre Region | Nyong-et-Mfoumou | Akonolinga | CPC | 2011 | |
a
Abbreviations: CDTUB, Centre de Dépistage et de Traitement de l'Ulcère de Buruli; CPC, Centre Pasteur du Cameroun; DRC, Democratic Republic of Congo; IME, Institut Médical Evangélique; KCCR, Kumasi Centre for Collaborative Research in Tropical Medicine; NCTC, National Collection of Type Cultures; PNLUB, Programme National de Lutte contre l'Ulcère de Buruli; YOI, year of isolation.