TABLE 2.
Regulation of genes in C. sakazakii treated by diallyl sulfide
| Regulation category and annotation cluster | Term and function | Fold enrichment | Benjamini FDR |
|---|---|---|---|
| Upregulation | |||
| 1 (enrichment score, 3.67) | GO:0051188; cofactor biosynthetic process | 1.62 | 0.01 |
| GO:0009108; coenzyme biosynthetic process | 1.71 | 0.01 | |
| GO:0042375; quinone cofactor metabolic process | 2.21 | 0.03 | |
| GO:0051186; cofactor metabolic process | 1.39 | 0.05 | |
| 2 (enrichment score, 2.96) | GO:0016051; carbohydrate biosynthetic process | 1.68 | 0.01 |
| GO:0000271; polysaccharide biosynthetic process | 1.73 | 0.01 | |
| GO:0008610; lipid biosynthetic process | 1.69 | 0.01 | |
| GO:0009103; lipopolysaccharide biosynthetic process | 2.05 | 0.05 | |
| GO:0008653; lipopolysaccharide metabolic process | 2.05 | 0.05 | |
| GO:0005976; polysaccharide metabolic process | 1.47 | 0.09 | |
| 3 (enrichment score, 2.83) | GO:0008360; regulation of cell shape | 2.34 | 0.01 |
| GO:0022604; regulation of cell morphogenesis | 2.34 | 0.01 | |
| GO:0000271; polysaccharide biosynthetic process | 1.73 | 0.01 | |
| GO:0009273; peptidoglycan-based cell wall biogenesis | 2.21 | 0.03 | |
| GO:0042546; cell wall biogenesis | 2.21 | 0.03 | |
| GO:0009252; peptidoglycan biosynthetic process | 2.27 | 0.04 | |
| GO:0006024; glycosaminoglycan biosynthetic process | 2.27 | 0.04 | |
| GO:0006023; aminoglycan biosynthetic process | 2.27 | 0.04 | |
| 4 (enrichment score, 2.52) | GO:0042375; quinone cofactor metabolic process | 2.21 | 0.03 |
| GO:0045426; quinone cofactor biosynthetic process | 2.18 | 0.04 | |
| GO:0006743; ubiquinone metabolic process | 2.73 | 0.05 | |
| Downregulation | |||
| 1 (enrichment score, 2.97) | GO:0005198; structural molecule activity | 3.97 | 0.02 |
| GO:0019843; rRNA binding | 6.51 | 0.01 | |
| GO:0003735; structural constituent of ribosome | 4.32 | 0.02 | |
| GO:0043232; intracellular non-membrane-bound organelle | 2.51 | 0.03 | |
| GO:0043228; non-membrane-bound organelle | 2.51 | 0.03 | |
| GO:0003723; RNA binding | 2.89 | 0.10 | |
| GO:0005840; ribosome | 3.15 | 0.04 | |
| GO:0030529; ribonucleoprotein complex | 3.08 | 0.03 | |
| 2 (enrichment score, 2.47) | GO:0042398; cellular amino acid derivative biosynthetic process | 6.87 | 0.16 |
| GO:0042401; biogenic amine biosynthetic process | 9.37 | 0.12 | |
| GO:0009309; amine biosynthetic process | 2.65 | 0.17 | |
| GO:0006576; biogenic amine metabolic process | 7.93 | 0.14 | |
| GO:0006577; betaine metabolic process | 20.61 | 0.25 | |
| GO:0006578; betaine biosynthetic process | 20.61 | 0.25 | |
| GO:0006575; cellular amino acid-derivative metabolic process | 4.12 | 0.31 |