FIG 3.

Lysis cassettes in the Nazgul-like phage type. Black boxes indicate unrelated genes of unknown function; gray and brown indicate o-spanin and i-spanin genes. Shades of gray and brown indicate sequence homology; diagonal hatching indicates endolysin genes. No sequence similarity is present among the five endolysin genes shown. The blue box in the Salvo endolysin gene indicates the N-terminal lipoprotein domain; vertical hatching indicates genes encoding proteins with at least one TMD, potentially holins or antiholins. Pink and yellow indicate sequence homology. Topological models of Sano, Salvo, Nazgul, AH2, and Chi membrane proteins are shown at the right. Genes are drawn to scale.