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Spanin gene architecture. Shown is a putative deletion (diagonal-hatched bar) that could convert the Sano-separated spanin gene pair into a Salvo-like overlapped gene pair. Gray areas connecting green domains show homologous domains of Salvo and Sano i-spanins (blue bars) and o-spanins (yellow bars). Orange sub-bars indicate lipoprotein signal sequences in o-spanins. Pink sub-bars indicate the TMD in i-spanin. The arrow indicates the direction of transcription.
