TABLE 1.
PRR expression on vaginal epithelial cells 4 days postinoculationa
| PRR | % positive cells per field (mean ± SEM) |
Pb | ||
|---|---|---|---|---|
| Inoculated, high PMNs | Inoculated, low PMNs | Uninoculated | ||
| SIGNR1 | 30.7 ± 5.9 | 9.97 ± 3.4 | 8.99 ± 1.7 | 0.022 |
| Mannose receptor | 2.6 ± 0.6 | 0.21 ± 0.02 | 0.408 ± 0.20 | 0.003 |
| TLR4 | 5.98 ± 1.9 | 6.49 ± 2.5 | 3.02 ± 1.2 | 0.87 |
a
Results are representative of 3 experiments with 4 to 6 mice per group.
b
Statistical analyses (Student's t test) were performed on data from the inoculated groups comparing animals with high PMNs to those with low PMNs. No positively stained epithelial cells were detected for TLR2 or dectin-1.