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Bpbs in WT and Bdkrb2-deficient micea
| Strain | No. of mice dead/total after challenge with BDK at: |
χ2 value, df | P value | |||
|---|---|---|---|---|---|---|
| 80 mg/kg | 40 mg/kg | 20 mg/kg | 10 mg/kg | |||
| C57BL/6J | 3/3 | 3/3 | 1/3 | 0/3 | ||
| B6.129S7-Bdkrb2tm1Jfh/J | 0/4 | 0/4 | 0/4 | 0/4 | 26.0, 7 | 0.0005 |
WT or Bdkrb2-deficient mice were sensitized with 200 ng PTX by i.v. injection and challenged 3 days later by i.v. injection of BDK. Significance was determined by Fisher's exact test.
