FIG 6.

ΔTgPL1-infected mice have higher cytokine levels at 8 weeks postinfection. The graphs are compilations of 3 independent experiments, with 3 uninfected age-matched control mice (uninf) (squares), 10 mice infected with WT parasites (diamonds), 12 mice infected with ΔTgPL1 parasites (circles), and 7 mice infected with complemented ΔTgPL1 parasites (comp) (triangles). Sera were collected at 8 weeks postinfection, and serum cytokine levels were assessed by cytometric bead array for the interleukin 12 heterodimer (IL-12p70) (A), TNF-α (B), IFN-γ (C), MCP-1 (D), IL-10 (E), and IL-6 (F). Each symbol represents cytokine levels from an individual mouse, and the horizontal bars indicate the mean of each group. *, P < 0.05; **, P < 0.01.