FIG 6.

Survival rates of mice infected by Streptococcus pneumoniae (Sp) with supernatant (Sup) of Prevotella intermedia (A), Fusobacterium nucleatum (B), and Porphyromonas gingivalis (C). All groups contained equal amounts of modified GAM broth and normal saline. The survival rates of S. pneumoniae-infected mice with PINU499 Sup were significantly lower than those of S. pneumoniae-infected mice without PiSup (†, P < 0.01). The survival rates of S. pneumoniae-infected mice with PgSup were significantly higher than those of S. pneumoniae-infected mice without PgSup (*, P < 0.05), whereas there was no significant difference between S. pneumoniae-infected mice with and without FnSup.