FIG 3.

Enhanced acquisition of CD4⁺ T cells in lung homogenates of Coccidioides-infected IL-10^−/− mice. Pulmonary cells were isolated from the nonvaccinated or vaccinated Coccidioides-infected WT and IL-10^−/− mice that were sacrificed at 8 DPC (A and C) or 12 DPC (B and D). Percentages of each immune cell subset within the gated CD45⁺ population were determined as described in Materials and Methods. Data are presented as means ± SEM of 4 mice per group. Asterisks indicate significant differences between the vaccinated and nonvaccinated mice of the same strain, while the dagger represents a significant difference between the IL-10^−/− and WT mice (P < 0.05).