Colonization data for C. difficile strains. (A) The percentage of strains that established as long-term colonizers in the gut microbiota of infants, shown separately for strains of ribotype 014, ribotype 001, other toxin-producing ribotypes, and toxin-negative ribotypes (non-tox; negative for tcdA, tcdB, and cdtA/B). *, P < 0.05; **, P < 0.01. (B and C) C. difficile population counts in fecal samples, shown separately for toxin-producing (toxin+) and toxin-negative (toxin-) strains (B) and for strains of ribotype 001 and all other strains (C) at 1, 2, and 4 weeks and 2, 6, and 12 months. *, P < 0.05.