TABLE 1.
C. difficile ribotypes detected in 42 Swedish children followed from birth to 1 to 3 years of age
| Nomenclature source and ribotype | Toxin gene carriagea |
Toxin B productionb | No. (%) of infants colonized | % of isolates | ||
|---|---|---|---|---|---|---|
| tcdA | tcdB | cdtA/B | ||||
| PHLSc | ||||||
| 001 | + | + | − | + | 19 (45) | 48 |
| 014 | + | + | − | + | 11 (26) | 19 |
| 020 | + | + | − | + | 2 (5) | 2 |
| 002 | + | + | − | + | 1 (2) | 2 |
| 012 | + | + | − | + | 1 (2) | 2 |
| 015 | + | + | − | + | 1 (2) | 0.5 |
| 046 | + | + | − | + | 1 (2) | 0.5 |
| 117 | + | + | − | + | 1 (2) | 1 |
| 131 | + | + | − | + | 1 (2) | 0.5 |
| SMId | ||||||
| SE2 | + | + | − | + | 1 (2) | 0.5 |
| SE5 | − | − | − | − | 1 (2) | 0.5 |
| SE6 | − | − | − | − | 1 (2) | 0.5 |
| SE14a | + | + | − | + | 1 (2) | 0.5 |
| SE21 | + | + | − | + | 1 (2) | 0.5 |
| SE36 | + | + | − | + | 1 (2) | 1 |
| This study | ||||||
| GI | − | − | − | − | 5 (12) | 5 |
| GII | − | − | − | − | 3 (7) | 3 |
| GIII | − | − | − | − | 3 (7) | 5 |
| GIV | − | − | − | − | 2 (5) | 5 |
| GV | − | − | − | − | 1 (2) | 2 |
| GVI | − | − | − | − | 1 (2) | 0.5 |
a
Isolates of C. difficile colonizing 42 Swedish infants were ribotyped and characterized regarding toxin gene carriage (presence [+] or absence [−] of tcdA, tcdB, and cdtA/B) in vitro. Toxin genes were identified by PCR (tcdA) or real-time PCR (tcdB and cdtA/B).
b
Toxin B production was determined in direct cell cytotoxicity neutralization assays.
c
PHLS Anaerobic Reference Unit (Cardiff, United Kingdom).
d
The Swedish Institute for Communicable Disease Control (http://www.smittskyddsinstitutet.se).