TABLE 2.
Mean time to detection and range of bacterial growth for the 7 tested Staphylococcus aureus reference strains in the presence of increasing concentrations of vancomycina
| Vancomycin phenotype | S. aureus strain | Mean (range) no. of hours to detection of heat production at indicated vancomycin concn (µg/ml) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 12 | 16 | ||
| VSSA | ATCC 29213 | <1 | <1 | 16.0 (14.5–15.7) | 59.6 (48.2–70.2) | |||||||
| VSSA | ATCC 43300 | <1 | <1 | 28.4 (25.1–34.3) | ||||||||
| hVISA | Mu3 | <1 | <1 | 4.4 (1.3–7.7) | 9.5 (6.7–12.4) | 19.9 (16.3–23.2) | 33.9 (16.8–45.1) | 43.4 (16.6–57.1) | ||||
| hVISA | PC1 | <1 | <1 | <1 | 5.2 (4.3–7.0) | 30.1 (13–51.6) | 56.2 (43.5–66.3) | |||||
| VISA | Mu50 | <1 | <1 | 1.1 (1.0–1.3) | 1.2 (1.0–1.4) | 3.3 (1.0–5.0) | 5.7 (4.5–6.7) | 8.3 (6.4–10.8) | 18.7 (15–25.5) | 29.9 (22.1–35.8) | 65.9 (58.5–72.0) | |
| VISA | PC3 | <1 | <1 | 1.1 (1.0–1.2) | 1.2 (1.0–1.5) | 1.2 (1.0–1.5) | 1.4 (1.0–2.3) | 1.8 (1.0–3.5) | 3.6 (3.0–4.4) | 4.7 (4.2–5.5) | 15.8 (7.3–26.5) | |
| VRSA | SA510 | <1 | <1 | <1 | 2.4 (1.0–3.1) | 3.5 (1.0–5.3) | 4.7 (1.4–6.5) | 5.6 (2.1–7.5) | 6.1 (2.1–8.3) | 6.5 (2.1–8.8) | 9.9 (8.5–10.9) | 11.4 (10.0–12.7) |
a
Empty cells represent vancomycin concentrations at which no growth was recorded during the 72 h of incubation.