TABLE 1.
Metabolic profiles of HFD-fed WT and TG mice
| Characteristic | Value for mice |
|
|---|---|---|
| WT | TGa | |
| Food intake (g/g of body wt/wk) | 0.62 ± 0.044 | 0.59 ± 0.044* |
| Liver wt (g) | 1.29 ± 0.061 | 1.05 ± 0.035* |
| Liver bile acid level (nmol/g of liver) | 473.9 ± 30.74 | 163.7 ± 83.90* |
| Serum bile acid level (μmol/liter) | 8.02 ± 0.82 | 3.717 ± 1.96* |
| Liver triglyceride concn (mg/g liver) | 74.58 ± 11.16 | 37.30 ± 8.75* |
| Serum cholesterol concn (mg/dl) | 109.1 ± 4.46 | 85.20 ± 2.93* |
| Fasting glucose level (mg/dl) | 130.3 ± 31.03 | 81.40 ± 7.82** |
| Serum insulin level (ng/ml) | 9.98 ± 2.59 | 6.96 ± 1.51* |
| HOMA-IR | 3.97 ± 0.48 | 1.516 ± 0.43* |
| Serum leptin level (ng/ml) | 17.43 ± 10.11 | 30.09 ± 1.75* |
| Oxygen consumption (dark phase) (ml/kg/h) | 2,813 ± 349.4 | 3,221 ± 570.6* |
a
Asterisks indicate significant differences from the WT (*, P < 0.05; **, P < 0.01).