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Binding of time-ordered GII.3 VLPs to human sera. The reactivity of serum IgG in human serum samples with the panel of time-ordered GII.3 VLPs was measured by ELISA and the results presented as an arbitrary concentration of bound IgG (y axis). The patient from whom each sample was collected is indicated (x axis). The bars represent the mean level of IgG bound to each VLP from two independent experiments. Error bars represent standard deviations.
