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Antigenicity of hantavirus VLPs. ELISA plates were activated with concentrated ANDV or PUUV VLPs, and their reactivity was tested with sera derived from patients infected with different hantavirus species (ANDV, PUUV, Sin Nombre virus [SNV]). A Student t test was used for statistical evaluation: ***, P < 0.00025; **, P < 0.0025; *, P < 0.025.
