FIG 9.

Link between changes in the number of potential glycosylation sites in the V1/V2 domain, V1/V2 length, Env incorporation, and fusion to MDDCs and CD4 T cells. Correlations between changes in the number of potential glycosylation sites identified by NX(T/S) and changes in V1/V2 length (A), Env incorporation (B), and fusion to MDDCs or resting or activated CD4 T cells (C) were determined. (D) Summary of the correlation between the changes incurred by the mutations for the four variables. Note that the four parameters were significantly correlated (P < 0.05, Spearman's test) for all comparisons except the relationship between Env incorporation and MDDC fusion (the changes in Env incorporation levels did not correlate with fusion).