FIG 4.

LANAC protection against mosquito-delivered WEEV challenge. (A) Mice (n = 5/group) were prime-boost vaccinated with E1ecto LANACs (LANAC) or sham LANACs (SHAM) and exposed to WEEV McMillan-infected Culex tarsalis mosquitoes. Survivorship was monitored for 21 days postinfection. Differences in the survival curves of mice immunized with E1ecto or sham LANACs were statistically significant (P = 0.0295). (B) Infectious virus titers in individual mosquitoes used to infect mice from each treatment group in panel A. Differences were not statistically significant.