FIG 8.
Passive transfer of pooled immune sera to nonimmunized mice. (A) Bioluminescence images of two mice, injected with either nonimmune (normal) mouse serum (NS) or 9-week immune serum (IS). Image acquisition occurred at specific times postinfection (104 PFU/dose of WEEV. McM.FLUC virus by the intranasal route). The mouse receiving NS was euthanized at 96 h postinfection. (B) Bioluminescence quantification (photons/second) of the four mice in each group treated prior to infection. Asterisks indicate statistically significant differences between treatment groups. (C) Survival curve for mice (n = 4/group) receiving IS or NS treatment prior to infection.