FIG 3.

A3 inhibits LCMV multiplication in A549 and BHK-21 cells. Subconfluent monolayers of A549 (A) and BHK-21 (B) cells were infected with LCMV (MOI, 0.01) and treated with the indicated concentrations of A3 (i) or ribavirin (Rib) (ii). Aliquots of TCS were obtained at the indicated times (hours postinfection) and titrated (resulting in data reported in FFU/ml) by using immunofluorescence. Dotted lines indicate the limits of detection for the assay. Viral infections were performed in triplicates. Mean values and standard deviations are shown. Statistical analyses were conducted using Student's t test within Microsoft Excel. *, P < 0.05.