FIG 3.
Comparative functional affinity of the HLA-Cw0801/Env171–180 epitope against known HBV epitopes. EBV-transformed B cells expressing specific HLA alleles were pulsed with different concentrations of the corresponding HBV epitopes and used as targets to stimulate in vitro expanded epitope-specific T cells. The dose-response curve was generated using IFN-γ production as a measurement of activation. The table below shows the interpolated EC50s of the various epitopes and the corresponding immunoprevalence of the response. Max, maximum.