Time dependence of population size and diversity (A) as well as mean distance to the MF sequence and the frequency of the MF (B). Parameter values were as follows: La = d = 2 aa, V0 = 1 × 104, U0 = 1 × 106, a = 1.0 × 10−3 day−1, b = 1.0 day−1, r0 = 20 day−1, μ = 1.0 × 10−5, and τ = 3 days.