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Dependence of jumping rate on the mutation rate for the WT-to-MF distance from 1 to 3 aa. Symbols represent averages and error bars represent 1 standard deviation over 100 realizations. Parameter values were as follows: V0 = 1 × 105, U0 = 1 × 106, a = 1.0 × 10−3 day−1, b = 0.1 day−1, r0 = 10 day−1, and τ = 3 days.
