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Virus titers in organs of mice following intraperitoneal infection with control and mutant VACV. Mice (n = 5 per group) were inoculated with 106 PFU of vD10rev, vD10stop, or vD10mu and sacrificed on day 5. Their organs were homogenized, and virus titers were determined by plaque assay on BS-C-1 cells. Statistical significance was determined by the Mann-Whitney test.
