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Morphological changes of human macrophages caused by three clades of H5N1 viruses. (A) Phase-contrast microscopy of macrophages infected with JS08 (clade 2.3.4), HB07 (clade 2.3.2), SY08 (clade 7), or mock control at an MOI of 0.1 for 12, 24, 36, and 48 h. (B) Scanning electron micrograph of human macrophages infected with JS08 (clade 2.3.4), HB07 (clade 2.3.2), SY08 (clade 7), or mock control at an MOI of 0.1 for 24 h.
