Table 1.
The effect of methotrexate and Ethyl pyruvate on wperm count, sperm viability, sperm maturity and DNA damage in mice (M±SE)
| Group | Sperm count (×106) | Sperm viability (%) | Sperm maturity (%) | Acridine orange+(%) |
|---|---|---|---|---|
| Control | 26.66±1.87 | 88.00±2.88 | 89.00±0.57 | 5.73±0.29 |
| MTX | 7.50± 1.15 a | 52.33±2.33 a | 90.33±1.76 | 12.66±1.4 a |
| EP | 25.94±0.81 b | 81.66±2.33 ab | 90.33±0.33 | 6.26±0.52 b |
| MTX+EP | 15.16±1.74 ab | 63.88±4.13 ab | 96.00±1.15 | 7.00±0.75 b |
a
Different significant (p<0.05) compared with control group
b
Different significant (p<0.05) compared with MTX group