TABLE 1.

Monocyte pathways regulated by M. bovis as determined by kinome arrays^a

Pathway	Database (protein identification)	P value of change (P ≤ 0.10)	Avg fold change
TLR (through NF-κB)	INOH (10068)	0.02	−1.6
NF-κB	PID BIOCARTA (3978)	0.02	−1.6
NF-κB activation	REACTOME (9204)	0.05	−1.7
IKK–NF-κB	INOH (10150)	0.05	−1.7
NF-κB activation	REACTOME (3767)	0.01	−1.8
Atypical NF-κB	PID NCI (9435)	0.05	−2.1
Canonical NF-κB	PID NCI (9358)	0.01	−1.5
Caspase cascade, apoptosis	PID NCI (9311)	0.04	−2.9
Apoptosis	REACTOME (1882)	0.06	−2.8
Gene expression of SOCS1	INOH (9782)	0.06	1.3
Gene expression SOCS1	INOH (10060)	0.06	1.3

^aKinome arrays were performed as indicated in Materials and Methods.