Skip to main content
. Author manuscript; available in PMC: 2014 Feb 3.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2007 Jul 6;293(3):H1877–H1882. doi: 10.1152/ajpheart.00516.2007

Table 1.

Hemodynamics in MHC-CREB-S133A and MHC-CREB-S133A-LZ NTG and TG mice

NTG CREB-S133A-LZ CREB-S133A
n 7 6 5
Heart rate, beats/min 538±25 612±23 611±28
Diastolic pressure, mmHg 95.5±6.4 89.4±4.2 66.6±3.0*,
Diastolic pressure, mmHg 65.4±6.3 61.9±5.8 54.3±3.6
dP/dtmax, mmHg/s 11,676±532 7,527 ±501* 6,480±189*
dP/dtmin, mmHg/s 12,151±550 8,316±625* 5,588±435*,

Values are means ± SE; n, number of animals. MHC, myosin heavy chain; TG, transgenic; NTG, nontransgenic; dP/dtmax and dP/dtmin, maximum and minimum first derivative of left ventricular (LV) pressure during contraction and relaxation, respectively.

*

P < 0.05 vs. NTG mice; and

P < 0.05 vs. cAMP response element binding protein (CREB)-S133A-leucine zipper (LZ) mice.