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Pg and fibrinogen consumption in human plasma
| PA | Pg consumption (EC50 nM) |
Fibrinogen consumption (EC50 nM) |
|---|---|---|
| TPA | 31.1 ± 1.1 | 10.1 ± 1.1 |
| SK | 1.8 ± 1.2* | 4.2 ± 1.1* |
| SKΔ1 | 16.8 ± 1.0* | 21.1 ± 1.1* |
| SKΔ59 | >500*† | >500*† |
P < 0.001 when compared with TPA.
The calculated EC50 exceeded the highest doses tested.
