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. Author manuscript; available in PMC: 2014 Feb 3.

Published in final edited form as: J Thromb Haemost. 2009 Jun 30;7(8):1321–1328. doi: 10.1111/j.1538-7836.2009.03491.x

Table 3.

Effect of fibrin (DD) E fragments on Pg activation by SKΔ1 and SKΔ59

	k_cat min⁻¹		K_m nM		k_cat/K_m μM⁻¹ min⁻¹
PA	−(DD) E	+(DD) E	−(DD) E	+(DD) E	−(DD) E	+(DD) E
SKΔ1	4.6 ± 0.6	4.9 ± 0.4	320 ± 70	96 ± 20	14.3	51.0
SKΔ59	NA^*	0.3 ± 0.0	NA^*	400 ± 70	NA^*	0.7
SK^†	20.0 ± 1.8	21.7 ± 0.8	458 ± 7	354 ± 2	43.6	61.3
TPA^†	1.6 ± 0.1	3.8 ± 0.1	331 ± 27	122 ± 14	4.8	31.5

^*

NA, no significant activity.

^†

As reported [54].